Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction
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چکیده
منابع مشابه
Post-Infarction Inflammation and Left Ventricular Remodeling
non-specific response to tissue damage.1 However, an investigation into the relation between the peak body temperature during the first week and in-hospital complications since the event of MI showed that the incidence of complications of pump failure (grade of class 2 or greater according to Killip’s classification or subset II or greater according to Forrester’s classification) and ventricula...
متن کاملLeft Ventricular Remodeling After Myocardial Infarction
Left ventricular remodeling is the process by which ventricular size, shape, and function are regulated by mechanical, neurohormonal, and genetic factors.1,2 Remodeling may be physiological and adaptive during normal growth or pathological due to myocardial infarction, cardiomyopathy, hypertension, or valvular heart disease (Figure 1). This article will review postinfarction remodeling, pathoph...
متن کامل[Left ventricular remodeling after myocardial infarction].
Left ventricular remodeling describes a number of geometric and structural changes that the left ventricle undergoes after myocardial infarction. Briefly, it comprises expansion of the infarct and dilatation of the healthy left ventricular segments. Its severity is related to the infarct size. These changes in ventricular geometry, in particular the dilatation, influence the long-term incidence...
متن کاملLeft Ventricular Diastolic Dyssynchrony in Post-Myocardial Infarction Patients: Does It Predict Future Left Ventricular Remodeling?
Left ventricular (LV) remodeling is well-known complication after myocardial infarction (MI) and numerous studies have emphasized the clinical importance of ventricular remod-eling. 1-4) In these literatures, progressive LV dilatation and decreased LV ejection fraction were major determinants in future development of heart failure and long term survival. That is why early recognition of patient...
متن کاملDirect Renin Inhibitor Attenuates Left Ventricular Remodeling in Post-Myocardial Infarction Heart Failure Mice.
BACKGROUND The role of direct renin inhibitors in myocardial ischemia-induced heart failure is controversial. We hypothesized that direct renin inhibitors play a positive role, affecting in vivo myocardial function as well as in vitro extracellular matrix change. METHODS Ten-week-old C57BL/6J male mice with 2-kidney 1-clip (2K1C) model were enrolled in this study. The mice were divided into 3...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2005
ISSN: 0008-6363
DOI: 10.1016/j.cardiores.2004.10.006